About Psilocybin
Psilocybin is a prodrug for the classical hallucinogen - more specifically, psychedelic - psilocin, or 4-HO-DMT , the active metabolite of psilocybin, responsible for all of the psychoactive effect of the drug. Both drugs are members of the indole and tryptamine classes. Psilocybin-containing mushrooms are used both recreationally, and traditionally, for spiritual purposes, as entheogens, with a history of use spanning millennia. It is produced by hundreds of species of fungi, including those of the genus Psilocybe, such as Psilocybe cubensis, Psilocybe semilanceata and Psilocybe cyanescens, and has also been reportedly isolated from about a dozen other genera. Collectively known as psilocybin mushrooms, these are commonly called "boomers," "sacred mushrooms," "magic mushrooms," or more simply "'shrooms." Possession, and in some cases usage, of psilocybin or psilocin has been outlawed in most countries across the globe. Proponents of its usage consider it to be an entheogen and a tool to supplement various types of practices for transcendence, including in meditation, psychonautics, and psychedelic psychotherapy. The intensity and duration of entheogenic effects of psilocybin mushrooms are highly variable, depending on species or cultivar of mushrooms, dosage, individual physiology, and set and setting.Once ingested, psilocybin is rapidly metabolised to psilocin, which then acts as a partial agonist at the 5-HT2A and 5-HT1A serotonin receptors in the brain. The mind-altering effects of psilocybin typically last anywhere from 3 to 8 hours; however, to individuals under the influence of psilocybin, the effects may seem to last much longer, since the drug can distort the perception of time.
The American banker and amateur mycologist R. Gordon Wasson and his wife Valentina discovered that the ancient religious practices of the Indians in a remote village of Mexico included ingestion of mushrooms. In 1957, they published an article in Life magazine , where they described the occurrence of hallucinatory experiences during these rituals. They were accompanied on a later expedition by the French mycologist Roger Heim, director of the musée national d'histoire naturelle, when it was possible to identify several of the fungi as Psilocybe species. Heim was able to successfully cultivate the mushroom in France, and sent samples to the Swiss chemist Albert Hofmann for analysis. Hofmann, who had in 1938 created LSD in his Sandoz laboratory, was the first to recognize the importance and chemical structure of the pure compounds he called psilocybin and psilocin. Leading a research group that was able to isolate and identify the compounds from Psilocybe mexicana, Hofmann was aided in the discovery process by his willingness to ingest mushroom extracts. He and his colleagues later synthesized a number of compounds chemically related to the naturally occurring psilocybin:
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Psilocybin Videos
Manna - psilocybin mushroom documentary
Mescaline vs. LSD vs. Psilocybin Mushrooms
Psilocybin Photos
Psilocybin - pazurescens.jpg
psilocybin - psilocybin.jpg
Psilocybin News
Police Seize Over 5 lbs. In Mushroom Growing Operation - KPHO Phoenix
 ABC15.com (KNXV-TV) | Police Seize Over 5 lbs. In Mushroom Growing Operation KPHO Phoenix Peoria and Avondale police arrested a man Wednesday for growing large amounts of Psilocybin mushrooms in his apartment. Police said 22-year-old Brandon ... Police Bust 'Magic Mushroom' Operation In Peoria Suspect behind mushroom growing operation arrested Undercover investigation turns up huge stash of 'shrooms |
New York Times Prints Hallucinogenic Paean to Mission Hipster Chicks - SF Weekly (blog)
New York Times Prints Hallucinogenic Paean to Mission Hipster Chicks SF Weekly (blog) ... reason than to see what a more literate version of Michael Kors might write after downing a bag of psilocybin mushrooms purchased in the Panhandle. ... |