About Ketamine

Ketamine is a drug used in human and veterinary medicine developed by Parke-Davis in 1962. Its hydrochloride salt is sold as Ketanest, Ketaset, and Ketalar. Pharmacologically, ketamine is classified as an NMDA receptor antagonist. At high, fully anesthetic level doses, ketamine has also been found to bind to opioid μ receptors and sigma receptors. Like other drugs of this class such as tiletamine and phencyclidine , it induces a state referred to as "dissociative anesthesia" and is used as a recreational drug.

Ketamine has a wide range of effects in humans, including analgesia, anesthesia, hallucinations, elevated blood pressure, and bronchodilation. Ketamine is primarily used for the induction and maintenance of general anesthesia, usually in combination with some sedative drug. Other uses include sedation in intensive care, analgesia , and treatment of bronchospasm. It is also a popular anesthetic in veterinary medicine.

Ketamine is a chiral compound. Most pharmaceutical preparations of ketamine are racemic; however, some brands reportedly have differences in enantiomeric proportions. The more active enantiomer, -ketamine, is also available for medical use under the brand name Ketanest S. Ketamine is a core medicine in the World Health Organization's "Essential Drugs List", which is a list of minimum medical needs for a basic health care system.

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bbc's Horizon Is alcohol worse than ecstasy? - Ketamine

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ASA Affiliated University Hospital Again Cited Over Dangerous Yet Common ... - PR Web (press release)


PR Web (press release)

ASA Affiliated University Hospital Again Cited Over Dangerous Yet Common ...
PR Web (press release)
Because there is no Level I study, the Cochrane ketamine report could not evaluate 'Goldilocks' PK anesthesia and translate it into a “specific treatment ...

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Hong Kong: Drug situation in 2009 - Webnewswire.com


Hong Kong: Drug situation in 2009
Webnewswire.com
Among the psychotropic substances abused, ketamine remained the most common.The number of reported ketamine abusers was 2.2% higher (from 5099 to 5212). ...
Fall in drug abusers recordedNews.gov.hk

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