About Ketamine
Ketamine is a drug used in human and veterinary medicine developed by Parke-Davis in 1962. Its hydrochloride salt is sold as Ketanest, Ketaset, and Ketalar. Pharmacologically, ketamine is classified as an NMDA receptor antagonist. At high, fully anesthetic level doses, ketamine has also been found to bind to opioid μ receptors and sigma receptors. Like other drugs of this class such as tiletamine and phencyclidine , it induces a state referred to as "dissociative anesthesia" and is used as a recreational drug.Ketamine has a wide range of effects in humans, including analgesia, anesthesia, hallucinations, elevated blood pressure, and bronchodilation. Ketamine is primarily used for the induction and maintenance of general anesthesia, usually in combination with some sedative drug. Other uses include sedation in intensive care, analgesia , and treatment of bronchospasm. It has been shown to be effective in treating depression in patients with bipolar disorder who have not responded to other anti-depressants. It is also a popular anesthetic in veterinary medicine.
Ketamine is a chiral compound. Most pharmaceutical preparations of ketamine are racemic; however, some brands reportedly have differences in enantiomeric proportions. The more active enantiomer, -ketamine, is also available for medical use under the brand name Ketanest S. However -ketamine is also active, and has differences in effects; the S enantiomer being a dissociative and the R enantiomer a hallucinogen. -ketamine, -ketamine & racemic -ketamine all have qualitatively separate distinct effect profiles, although S has the most active potency. Ketamine is a core medicine in the World Health Organization's "Essential Drugs List", which is a list of minimum medical needs for a basic health care system.
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Ketamine News
Ketamine fights depression, so does vitamin D - Food Consumer
 Telegraph.co.uk | Ketamine fights depression, so does vitamin D Food Consumer Yale University researchers have found a new pathway that explains why antidepressant ketamine works to relieve depressive symptoms in a matter of hours ... Ketamine is 'magic drug' for depression The Anti-Depressant Secrets of Ketamine 'Party drug' for depression? |
Extra-special: Ketamine is 'magic' drug for treating severe depression - New York Daily News
 New York Daily News | Extra-special: Ketamine is 'magic' drug for treating severe depression New York Daily News A Yale University medical team is touting ketamine - aka the recreational drug Special K - as the latest miracle drug for the treatment ... Can horse tranquilizers cure depression? |